The 23rd Street Fire was an incident that took place on October 17, 1966 in the New York City borough of Manhattan, when a group of firefighters from the New York City Fire Department responding to a fire at 7 East 22nd Street entered a building at 6 East 23rd Street as part of an effort to fight the fire. Twelve firefighters were killed after the floor collapsed, the largest loss of life in the department's history until the collapse of the World Trade Center in the September 11, 2001 terrorist attacks.