Pueblo Revolt

The Pueblo Revolt of 1680, or Popé's Rebellion, was an uprising of most of the Pueblo Indians against the Spanish colonizers in the province of Santa Fe de Nuevo México, present day New Mexico. The Pueblo killed 400 Spanish and drove the remaining 2,000 settlers out of the province. Twelve years later the Spanish returned and were able to reoccupy New Mexico with little opposition.

• http://en.wikipedia.org/wiki/Pueblo Revolt