The Hagood-Mauldin House is a property listed on the National Register of Historic Places located in Pickens, South Carolina. The house was originally constructed for James Earle Hagood ca.1856 in the town of Old Pickens but in 1868 when the Pickens District was divided into Oconee County and Pickens County, the house was disassembled, boards and beams numbered, and reassembled at its present location in the town of Pickens.