Acarnania thereafter came under Macedonian rule. In 314 BC, at the behest of the Macedonian king Cassander, the settlements of Acarnania lying near the Aetolian border were conglomerated into fewer, larger settlements. Still, border conflicts with the Aetolians were frequent, and led to Acarnania's territory being partitioned between Aetolia and Epirus, c.250 BC. After the fall of the king of Epirus, the Acarnanian territory that had been given to Epirus regained its independence, and Leucas became the capital of the region.