COSI (an acronym for Center of Science and Industry) is a science museum and research center located in Columbus, Ohio in the United States. Originally opened in 1964, COSI was relocated to a 320,000 square foot state-of-the-art facility designed by Japanese architect Arata Isozaki along a bend in the Scioto River in 1999. COSI features more than 300 interactive exhibits throughout themed exhibition areas.