The Limpinwood Nature Reserve is a protected nature reserve that is located on the Northern Rivers region of New South Wales, in eastern Australia. The reserve was gazetted in April 1963 with additions made in 1967, over former fauna and crown reserves, and further additions were made in 1988 to make the reserve to its current area of 2,646 hectares (6,540 acres). The reserve is situated north-west of the rural locality of Limpinwood, and north of Tyalgum and defines part of the state border between New South Wales and Queensland.