The car chase scene down the steps - Barbara Streisand and Ryan O'Neal are in the front car.
What's Up, Doc? is a 1972 screwball comedy film released by Warner Bros., directed by Peter Bogdanovich and starring Barbra Streisand, Ryan O'Neal, and Madeline Kahn in her first feature film role (for which she was nominated for a Golden Globe). It was intended to pay homage to comedy films of the 1930s, especially Bringing Up Baby, as well as old Bugs Bunny cartoons (another WB product).