The Cattle Bank is a historic bank building located at 102 E. University Ave. in Champaign, Illinois. Built in the late 1850s, the building is the oldest extant commercial building in Champaign. It opened as a branch of the Grand Prairie Bank, Urbana's first bank. Champaign was the southern terminus of a railroad line to Chicago, so cattle raisers from the surrounding area drove their cattle to Champaign to ship them to the Chicago market. The Cattle Bank provided banking and loan services to these cattlemen.